Featured Stories
Sartorius and Sanofi Collaborate on Bioprocess Intensification
Sartorius has partnered with Sanofi to develop an integrated continuous biomanufacturing (ICB) platform to enhance downstream bioprocessing through the combination of Sartorius' engineering expertise with Sanofi's ICB prototypes and patents.
When will AI Solve the Drug Discovery Challenge?
Google DeepMind, in collaboration with Isomorphic Labs, has introduced AlphaFold 3 - the latest iteration of its AI model for biological research and drug discovery.
Research Shows That Aspirin Could Help Prevent Colon Cancer
A study reveals that regular aspirin use may protect against colorectal cancer by boosting the immune system's surveillance of tumor cells. Researchers found that aspirin users had less cancer spread and higher immune cell infiltration in tumors.
Mundipharma and Vectura to Develop Environment-Friendly Flutiform Inhaler
Following their existing lab-scale development partnership, global healthcare company Mundipharma and Vectura, the specialist inhalation CDMO, have announced they are to progress development of a more environmentally friendly reformulation of FLUTIFORM (fluticasone propionate/formoterol fumarate) pressurised metered-dose inhaler (pMDI).
AbbVie's Qulipta Shows Long-Term Promise for Migraine Prevention
The first and only oral CGRP receptor antagonist approved in the U.S. for preventing both episodic and chronic migraines in adults. The Phase 3 study of Qulipta (atogepant) demonstrated significantly reduced monthly migraine days compared to placebo over a 12-week period.
Bloom Biorenewables and Valsynthèse Scale Up Sustainable Lignin Production for Polyurethane
Bloom Biorenewables have recently announced the successful completion of a production campaign in partnership with custom synthesis and contract manufacturer, Valsynthèse. This collaboration has led to significant advancements in scaling up aldehyde-assisted fractionation (AAF) technology to produce uncondensed lignin, a common feedstock used directly in polyurethane materials.
Wegovy and Similar Weight Loss Drugs Explored as Potential Treatment for Heart Failure in Diabetic and Obese Patients
Another positive story for GLP-1 weight loss drugs has been announced, suggesting medications like Wegovy may have potential benefits in treating heart failure among patients with obesity and diabetes. Typically prescribed for weight management in high-risk populations, this positive news is likely to continue the high demand for these drug substances.
Rezdiffra Launches as First MASH Treatment with Promising Rapid Uptakes
Madrigal Pharmaceuticals' new drug, Rezdiffra, has recently been approved as the first treatment for metabolic dysfunction-associated steatohepatitis (MASH). Gastroenterologists, are highly optimistic about its potential in managing patients with moderate to advanced fibrosis and suffering from severe liver conditions such as cirrhosis.
Moderna Broadens Horizon with Promising Trials for New Vaccines
Expanding beyond its COVID-19 vaccines, Moderna reported positive trial results for vaccines against norovirus, Epstein-Barr virus, and Varicella-Zoster virus, aiming for final-stage studies and marketing a positive move towards diversifying its product.
Amgen's MariTide Challenges Weight Loss Drug Market with Innovative Approach and Promising Early Results
Amgen's MariTide shows promising results in early-stage trials, offering a novel approach to weight loss by both activating and blocking gastric inhibitory polypeptide (GIP) receptors, potentially mimicking the body's natural regulation process.
Redx Pharma Clinical Trial for Pioneering Crohn's Disease Medication
Redx Pharma has initiated a Phase I clinical trial for RXC008, a new class of ROCK inhibitor aimed at treating fibrostenotic Crohn's disease. This study, focusing on safety and pharmacokinetics, marks a significant step in addressing a condition currently limited to surgical interventions. Results are anticipated by year's end.
Janux Therapeutics Value Increases Upon Trial Results
Janux Therapeutics' stock value soared after early trial results suggested its immunotherapy technology could offer potent, safer treatments for solid tumors.
Viking Therapeutics' Obesity Drug Exceeds Competitors
Viking Therapeutics' weight loss drug showed up to 15% body weight reduction in a 13-week mid-stage trial, surpassing similar drugs from Eli Lilly and Novo Nordisk. However, further validation is needed in Phase 3 trials.
GSK Demonstrates Advanced-Phase Gonorrhea Success
GSK's oral antibiotic, gepotidacin, has shown effectiveness in a late-stage gonorrhea trial, matching the current treatment regimen's success. It's also under consideration for urinary tract infections, with approvals sought later this year.
Zealand Pharma Announces Obesity Success with Liver Disease Treatment
Zealand Pharma's stock soared after announcing positive Phase 2 trial results for survodutide, a liver disease treatment with potential in the obesity market.
IQVIA Global Trends in R&D 2024 Report
IQVIA has published a report "Global Trends in R&D 2024" exploring current developments and prospects in pharmaceutical research and development.
Nanoform Wins Business Finland Grant of EUR 4.3M for its R&D in Nanoparticle-Enabled Formulation
Nanoform, the medicine performance-enhancing company, announced that it has won a grant of up to 4.3 million euros from Business Finland, the Finnish government organization for innovation funding and trade.
Lantern Pharma Progresses Novel ADC Initiative in Various Solid Cancer Types
Lantern Pharma is advancing a new ADC program aimed at various solid tumor cancers. The program which uses a cryptophycin-based ADC has already shown very high potency in preclinical tests.
BMS Pay $674m for Generative AI Drug Discovery
Bristol Myers Squibb (BMS) has partnered with deep tech company VantAI in a $674 million deal for its Generative AI-driven drug discovery platform.
European Commission Approves First CRISPR Gene-Edited Therapy for Blood Disorder
The European Commission has approved CASGEVY™ (exagamglogene autotemcel) - the first CRISPR/Cas9 gene-edited therapy, for treating severe sickle cell disease (SCD) and transfusion-dependent beta thalassemia (TDT) in patients aged 12 and older.