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Biopharma Demand Continues to Fuel CDMO Services Growth

Novo’s proposed acquisition of Catalent, with the immediate goal of adding capacity for its weight-loss drugs, has rarely been out of the news, whilst a raft of expansions elsewhere has been announced at Thermo Fisher, Alcami, Lonza and Vetter, to list but a few.

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Mundipharma and Vectura to Develop Environment-Friendly Flutiform Inhaler

Following their existing lab-scale development partnership, global healthcare company Mundipharma and Vectura, the specialist inhalation CDMO, have announced they are to progress development of a more environmentally friendly reformulation of FLUTIFORM (fluticasone propionate/formoterol fumarate) pressurised metered-dose inhaler (pMDI).

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Bloom Biorenewables and Valsynthèse Scale Up Sustainable Lignin Production for Polyurethane

Bloom Biorenewables have recently announced the successful completion of a production campaign in partnership with custom synthesis and contract manufacturer, Valsynthèse. This collaboration has led to significant advancements in scaling up aldehyde-assisted fractionation (AAF) technology to produce uncondensed lignin, a common feedstock used directly in polyurethane materials.

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Wegovy and Similar Weight Loss Drugs Explored as Potential Treatment for Heart Failure in Diabetic and Obese Patients

Another positive story for GLP-1 weight loss drugs has been announced, suggesting medications like Wegovy may have potential benefits in treating heart failure among patients with obesity and diabetes. Typically prescribed for weight management in high-risk populations, this positive news is likely to continue the high demand for these drug substances.

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Rezdiffra Launches as First MASH Treatment with Promising Rapid Uptakes

Madrigal Pharmaceuticals' new drug, Rezdiffra, has recently been approved as the first treatment for metabolic dysfunction-associated steatohepatitis (MASH). Gastroenterologists, are highly optimistic about its potential in managing patients with moderate to advanced fibrosis and suffering from severe liver conditions such as cirrhosis.

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Redx Pharma Clinical Trial for Pioneering Crohn's Disease Medication

Redx Pharma has initiated a Phase I clinical trial for RXC008, a new class of ROCK inhibitor aimed at treating fibrostenotic Crohn's disease. This study, focusing on safety and pharmacokinetics, marks a significant step in addressing a condition currently limited to surgical interventions. Results are anticipated by year's end.

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GSK Demonstrates Advanced-Phase Gonorrhea Success

GSK's oral antibiotic, gepotidacin, has shown effectiveness in a late-stage gonorrhea trial, matching the current treatment regimen's success. It's also under consideration for urinary tract infections, with approvals sought later this year.

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