Sartorius and Sanofi Collaborate on Bioprocess Intensification

Sartorius has partnered with Sanofi to develop an integrated continuous biomanufacturing (ICB) platform to enhance downstream bioprocessing through the combination of Sartorius' engineering expertise with Sanofi's ICB prototypes and patents. It is claimed the ICB streamlines production by maintaining a continuous flow of materials, increasing efficiency, reducing waste, and lowering raw material and energy consumption, with the goal being to reduce drug manufacturing expenses, improve environmental sustainability, and expedite delivery of biologics.

The following article originally appeared in GEN.

Sartorius is collaborating with Sanofi to develop an end-to-end platform for integrated and continuous downstream bioprocessing (ICB). Sartorius will contribute its engineering and manufacturing expertise to commercialize ICB platforms based on prototypes developed by Sanofi. In return, Sanofi will grant Sartorius exclusive access to its know-how and patents related to the ICB platform.

“Technological innovation is crucial for biopharmaceutical companies to significantly reduce the cost of drug manufacturing, while improving the environmental footprint of their operations, and ultimately getting life-saving drugs to patients faster,” said Jan Schäfer head of separation systems at Sartorius. “As the biologics landscape becomes more diverse, teaming up with Sanofi is an excellent basis for developing a unique modular platform that combines flexibility with the advantages of intensified bioprocessing.

Integrated continuous biomanufacturing is an advanced approach to the production of biopharmaceuticals. The concept aims to maximize efficiency by enabling uninterrupted and steady materials flow, as opposed to traditional batch methods, and by integrating multiple unit operations into a lean process setup. ICB reduces the overall process footprint, leading to lower raw material and energy consumption, higher productivity, and less waste.

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