Following a previous announcement just a few days earlier that it would layoff 158 of its workers, Ginkgo Bioworks, the cell programming company, expanded the number of people affected to 400, or around 35% of its workforce.

Eli Lilly has announced a partnership with OpenAI to leverage generative AI to invent novel antimicrobials to address drug-resistant pathogens and their worldwide impact on antimicrobial resistance.

The collaboration comes through the initiative of Lilly’s Social Impact Venture Capital Portfolio, with $100mn committed to provide patients with two to four new antibiotics by 2030.

Two CDMOs, Abzena and Argonaut Manufacturing Services, have announced a strategic partnership to provide an integrated drug substance and product manufacturing solution for biopharmaceutical companies to streamline drug development from early discovery to commercial manufacturing.

NeuroBo has recently announced pre-clinical data for its drug candidate DA-1726, demonstrated superiority in weight loss, retention of lean body mass, and lipid-lowering effects compared to Boehringer Ingelheim’s survodutide, in pre-clinical models.

Zealand Pharma has sold $1bn worth of new shares as it sets out to invest in the development of obesity pipeline candidates including amylin analogue petrelintide and the GLP-1/GLP-2 receptor dual agonist dapiglutide.

Indian multinational pharmaceutical company, Lupin, has expanded into the CDMO market.

The company has appointed Abdelaziz Toumi as the CEO of its newly established subsidiary, Lupin Manufacturing Solutions (LMS) which will focus on developing, manufacturing, and selling APIs while expanding into the CDMO market.

It wasn’t so very long ago that progress in delivering systemic treatments, via new oral technologies, inhalables and via a plethora of alternative routes of delivery suggested that the days were numbered for invasive injections, but recent reports now suggests injectables will remain a mainstay of drug delivery for some time to come.

With plenty of panels happening at BIO 2024, one convention discussion highlighted the transformative potential of gene therapy and the challenges of funding these high-cost, one-time treatments. Experts from bluebird bio, Vertex Pharmaceuticals, and other stakeholders emphasized the need for innovative payment models that reflect the long-term value of gene therapies.

GSK has secured a non-exclusive license to Elsie Biotechnologies' oligonucleotide discovery platform following a successful research collaboration.

Thermo Fisher Scientific has inaugurated a GMP-certified ultra-cold facility in Bleiswijk, Netherlands, to enhance its clinical trial network in Europe. This state-of-the-art facility supports the development of advanced therapies, including cell and gene therapies, biologics, and vaccines through comprehensive services, including ambient to cryogenic storage, clinical packaging, labeling, and distribution.

Kindeva Drug Delivery, the drug and device CDMO, is to expanding its facilities at its Charnwood campus in Loughborough, U.K. The expansion will support growth in demand for so-called green propellants, providing commercial-scale supply and doubling the company’s UK laboratory footprint.

The company will move its development services site from Skokie to Des Plaines, Illinois, where a construction project was announced to add new buildings for clinical manufacturing and related services. Vetter will also expand its commercial business at its 125-acre site in Saarland, Germany, to meet increasing customer demand for high quality injectables.

Sharp Services announced a significant expansion of its Macungie, Pennsylvania site, doubling its size to 315,000 square feet and enhancing production capacity for sterile injectable secondary packaging, including vial labeling, pre-filled syringe assembly, and autoinjector packaging. The expansion - driven by increasing demand for biologics and injectable medicines - will also add new packaging suites, cold storage, and create 75-100 new jobs.

Japan headquartered chemicals group, Asahi Kasei, is expanding its Bionova CDMO’s services to include plasmid DNA (pDNA) production for cell and gene therapy developers by establishing a new facility in The Woodlands, Texas, where it is set to begin research-grade pDNA production in early 2025 and GMP manufacturing later that year.

The San Francisco-based biotech secured $225 million to further develop its immune checkpoint enhancer, ALTB-268. This novel therapy aims to treat autoimmune and inflammatory diseases by regulating overactive immune responses without affecting normal immune defenses.

To meet increased market demand for parenteral manufacturing, leading CDMO Alcami has announced the strategic expansion of its sterile fill-finish manufacturing capabilities and capacity for a total of six fill-finish lines.

The Indianapolis-based drugmaker has announced it will increase its investment at its newest, 600-acre Lebanon, Indiana, site by $5.3 Bn, where it will make tirzepatide, the API used for its type-2 diabetes drug Mounjaro and obesity treatment Zepbound.

Sanofi has announced a collaboration with OpenAI, the ChatGPT parent, and Formation Bio, a technology-driven drug developer with a pipeline of drug assets, to accelerate drug development.

AstraZeneca has set an ambitious goal to achieve $80 bn in revenue by 2030, following on from their successful strategy that managed to generate $45 bn in revenue in 2023.

The Biotechnology Innovation Organization (BIO) has announced a significant restructuring initiative, which includes laying off staff to streamline operations to enhance the group's lobbying effectiveness at better supporting the biotechnology industry.